Renal protection in IgA nephropathy requires strict blood pressure control

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Renal protection in IgA nephropathy requires strict blood pressure control.

Primary IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide [1,2]. Although IgAN was considered a benign condition for many years, we now know that many cases eventually progress to end-stage renal failure. According to recent reviews, the actuarial renal survival at 10 years is 80–85% in most studies. Moreover, 30–40% of affected individuals develop end-stage...

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Blood pressure control in diabetic nephropathy.

Epidemiologic studies show a worldwide diabetic epidemic. Diabetes mellitus is associated with a reduced life span due to macrovascular and Microvascular complications. Thus, diabetic nephropathy, which is the major cause of morbidity and mortality for patients with either type 1 diabetes mellitus or type 2 diabetes mellitus, is a public health care problem. Blood pressure control is a proven i...

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Long-term improvement in renal function after short-term strict blood pressure control in hypertensive nephrosclerosis.

Seventy-nine hypertensive nephrosclerosis patients entered a prospective randomized single-blind study to 1) establish the pattern of decay of renal function in this population and the variability therein and 2) to determine if strict diastolic blood pressure (DBP) control (less than or equal to 80 mm Hg) is more effective than conventional levels (90-95 mm Hg) in conserving renal function. Bec...

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Renal vascular lesions in IgA nephropathy

V lesions are of principal importance in the progression of various primary and secondary kidney diseases (1). In the majority of individuals with kidney diseases, vascular component, is involved secondarily in the disease process affecting primarily the glomeruli. Indeed, in IgAN as a common and progressive glomerulopathy, impaired kidney function, hypertension, proteinuria and interstitial fi...

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Effect of strict blood pressure control on proteinuria in renal patients treated with different antihypertensive drugs.

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2005

ISSN: 1460-2385,0931-0509

DOI: 10.1093/ndt/gfh920